Rare and Low Frequency Variant Stratification in the UK Population: Description and Impact on Association Tests

Although variations in allele frequencies at common SNPs have been extensively studied in different populations, little is known about the stratification of rare variants and its impact on association tests. In this paper, we used Affymetrix 500K genotype data from the WTCCC to investigate if varian...

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Main Authors: Babron, Marie-Claude, de Tayrac, Marie, Rutledge, Douglas N., Zeggini, Eleftheria, Génin, Emmanuelle
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465327/
https://ncbi.nlm.nih.gov/pubmed/23071581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046519
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