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Cholesterol synthesis in polyclonally activated cytotoxic lymphocytes and its requirement for differentiation and proliferation.

The kinetics of sterol synthesis and DNA synthesis in polyclonally activated, concanavalin A-stimulated spleen cell cultures were analyzed. Inhibition of DNA synthesis by 1-beta-D-arabinofuranosylcytosine (Ara-C) did not abrogate the formation of cytotoxic effector cells. However, inhibition of ster...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Heiniger, H J, Marshall, J D
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346520/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.12.3823
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