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Polyclonal activation of B lymphocytes by lipopolysaccharide requires macrophage-derived interleukin-1.

Lipopolysaccharide (LPS) is a potent murine polyclonal B-cell activator which induces cellular proliferation and IgM secretion. The precise role of activated macrophages in the induction of LPS-dependent, B-cell responses has been unclear. Although early reports concluded that the LPS effect occurs...

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Autor principal: Bucala, R
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421668/
https://ncbi.nlm.nih.gov/pubmed/1493918
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