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Mislocalized Opsin and cAMP Signaling: A Mechanism for Sprouting by Rod Cells in Retinal Degeneration

PURPOSE. In human retinal degeneration, rod photoreceptors reactively sprout neurites. The mechanism is unknown in part because of the paucity of animal models displaying this feature of human pathology. We tested the role of cAMP and opsin in sprouting by tiger salamander rod cells, photoreceptors...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Jianfeng, Zhang, Nan, Beuve, Annie, Townes-Anderson, Ellen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Association for Research in Vision and Ophthalmology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465016/
https://ncbi.nlm.nih.gov/pubmed/22899763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10180
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