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Mislocalized Opsin and cAMP Signaling: A Mechanism for Sprouting by Rod Cells in Retinal Degeneration
PURPOSE. In human retinal degeneration, rod photoreceptors reactively sprout neurites. The mechanism is unknown in part because of the paucity of animal models displaying this feature of human pathology. We tested the role of cAMP and opsin in sprouting by tiger salamander rod cells, photoreceptors...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Association for Research in Vision and Ophthalmology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465016/ https://ncbi.nlm.nih.gov/pubmed/22899763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10180 |
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