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Activation of mislocalized opsin kills rod cells: A novel mechanism for rod cell death in retinal disease

Rod photoreceptors are highly compartmentalized sensory neurons that maintain strict ultrastructural and molecular polarity. Structural subdivisions include the outer segment, inner segment, cell body, and synaptic terminal. The visual pigment rhodopsin is found predominantly in membranes of the rod...

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Autors principals: Alfinito, Peter D., Townes-Anderson, Ellen
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122826/
https://ncbi.nlm.nih.gov/pubmed/11943854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072557799
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