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Activation of mislocalized opsin kills rod cells: A novel mechanism for rod cell death in retinal disease

Rod photoreceptors are highly compartmentalized sensory neurons that maintain strict ultrastructural and molecular polarity. Structural subdivisions include the outer segment, inner segment, cell body, and synaptic terminal. The visual pigment rhodopsin is found predominantly in membranes of the rod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alfinito, Peter D., Townes-Anderson, Ellen
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC122826/
https://ncbi.nlm.nih.gov/pubmed/11943854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072557799
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