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Activation of mislocalized opsin kills rod cells: A novel mechanism for rod cell death in retinal disease

Rod photoreceptors are highly compartmentalized sensory neurons that maintain strict ultrastructural and molecular polarity. Structural subdivisions include the outer segment, inner segment, cell body, and synaptic terminal. The visual pigment rhodopsin is found predominantly in membranes of the rod...

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Detalles Bibliográficos
Main Authors: Alfinito, Peter D., Townes-Anderson, Ellen
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC122826/
https://ncbi.nlm.nih.gov/pubmed/11943854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072557799
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