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Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene

Retinitis pigmentosa (RP), a common group of human retinopathic diseases, is characterized by late-onset night blindness, loss of peripheral vision, and diminished or absent electroretinogram (ERG) responses. Mutations in the photoreceptor-specific gene RP1 account for 5–10% of cases of autosomal do...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Gao, Jiangang, Cheon, Kyeongmi, Nusinowitz, Steven, Liu, Qin, Bei, Di, Atkins, Karen, Azimi, Asif, Daiger, Stephen P., Farber, Debora B., Heckenlively, John R., Pierce, Eric A., Sullivan, Lori S., Zuo, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122834/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11960024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.042122399
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