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Production and characterization of monoclonal antibodies to rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Rat liver microsomal 3-hydroxy-3-methylglutaryl-CoA reductase [HMG-CoA reductase; mevalonate:NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34], the key regulatory enzyme in cholesterol biosynthesis, has been purified to apparent homogeneity. Purified HMG-CoA reductase yields a single diffuse band w...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Clark, R E, Martin, G G, Barton, M C, Shapiro, D J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1982
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346501/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954516/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.12.3734
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