Production and characterization of monoclonal antibodies to rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Rat liver microsomal 3-hydroxy-3-methylglutaryl-CoA reductase [HMG-CoA reductase; mevalonate:NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34], the key regulatory enzyme in cholesterol biosynthesis, has been purified to apparent homogeneity. Purified HMG-CoA reductase yields a single diffuse band w...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Clark, R E, Martin, G G, Barton, M C, Shapiro, D J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1982
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC346501/
https://ncbi.nlm.nih.gov/pubmed/6954516
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