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Intramolecular Diels–Alder Reactions of Cycloalkenones: Translation of High endo Selectivity to trans Junctions

Intramolecular Diels–Alder (IMDA) reactions of cyclobutenone and larger cycloalkenones are described. High levels of endo addition attained from Lewis acid catalysis translate to trans hydrindene junctions upon fragmentation of the tricyclic adducts.

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Detalhes bibliográficos
Main Authors: Ross, Audrey G., Li, Xiaohua, Danishefsky, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464979/
https://ncbi.nlm.nih.gov/pubmed/22950514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307708q
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