Cooperative benefit for the combination of rapamycin and imatinib in tuberous sclerosis complex neoplasia

Tuberous sclerosis (TS) is a common autosomal-dominant disorder characterized by tumors of the skin, lung, brain, and kidneys. Monotherapy with rapamycin however resulted in partial regression of tumors, implying the involvement of additional pathways. We have previously implicated platelet-derived...

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Detalhes bibliográficos
Main Authors: Govindarajan, Baskaran, Willoughby, Laura, Band, Hamid, Curatolo, Adam S, Veledar, Emir, Chen, Suephy, Bonner, Michael Y, Abel, Martin-Garrido, Moses, Marsha A, Arbiser, Jack L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464934/
https://ncbi.nlm.nih.gov/pubmed/22765013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-4-11
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