Cooperative benefit for the combination of rapamycin and imatinib in tuberous sclerosis complex neoplasia

Tuberous sclerosis (TS) is a common autosomal-dominant disorder characterized by tumors of the skin, lung, brain, and kidneys. Monotherapy with rapamycin however resulted in partial regression of tumors, implying the involvement of additional pathways. We have previously implicated platelet-derived...

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Main Authors: Govindarajan, Baskaran, Willoughby, Laura, Band, Hamid, Curatolo, Adam S, Veledar, Emir, Chen, Suephy, Bonner, Michael Y, Abel, Martin-Garrido, Moses, Marsha A, Arbiser, Jack L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464934/
https://ncbi.nlm.nih.gov/pubmed/22765013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-4-11
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