Cooperative benefit for the combination of rapamycin and imatinib in tuberous sclerosis complex neoplasia

Tuberous sclerosis (TS) is a common autosomal-dominant disorder characterized by tumors of the skin, lung, brain, and kidneys. Monotherapy with rapamycin however resulted in partial regression of tumors, implying the involvement of additional pathways. We have previously implicated platelet-derived...

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Détails bibliographiques
Auteurs principaux: Govindarajan, Baskaran, Willoughby, Laura, Band, Hamid, Curatolo, Adam S, Veledar, Emir, Chen, Suephy, Bonner, Michael Y, Abel, Martin-Garrido, Moses, Marsha A, Arbiser, Jack L
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464934/
https://ncbi.nlm.nih.gov/pubmed/22765013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-4-11
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