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Rapamycin for treating Tuberous Sclerosis and Autism Spectrum Disorders
Tuberous sclerosis (TSC) is a genetic disorder caused by heterozygous mutations in the TSC1 or TSC2 genes and is associated with autism spectrum disorders (ASD) in 20–60% of cases. In addition, altered TSC/mTOR signaling is emerging as a feature common to a subset of ASD. Recent findings, in animal...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075964/ https://ncbi.nlm.nih.gov/pubmed/21115397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2010.10.002 |
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