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Incorporation of the B18R Gene of Vaccinia Virus Into an Oncolytic Herpes Simplex Virus Improves Antitumor Activity

Interferon (IFN) antiviral defense mechanism plays a critical role in controlling virus infection. It thus represents a formidable hurdle for virotherapy. Despite the reported ability of herpes simplex virus (HSV) to counteract this defense, the duration and extent of HSV infection in vivo is still...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fu, Xinping, Rivera, Armando, Tao, Lihua, Zhang, Xiaoliu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464635/
https://ncbi.nlm.nih.gov/pubmed/22692498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.113
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