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A Short Polypeptide from the Herpes Simplex Virus Type 2 ICP10 Gene Can Induce Antigen Aggregation and Autophagosomal Degradation for Enhanced Immune Presentation

It has been reported that certain polypeptides derived from aggregation-prone cellular proteins can turn soluble green fluorescent protein (GFP) into aggregates. Here we report our finding that a short peptide derived from a viral gene, ICP10 of herpes simplex virus (HSV)-2, also possesses such a pr...

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Detalhes bibliográficos
Main Authors: Fu, Xinping, Tao, Lihua, Zhang, Xiaoliu
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999574/
https://ncbi.nlm.nih.gov/pubmed/20583863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.080
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