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Phosphoinositide-3-kinase/akt - dependent signaling is required for maintenance of [Ca(2+)](i,)I(Ca), and Ca(2+) transients in HL-1 cardiomyocytes

The phosphoinositide 3-kinases (PI3K/Akt) dependent signaling pathway plays an important role in cardiac function, specifically cardiac contractility. We have reported that sepsis decreases myocardial Akt activation, which correlates with cardiac dysfunction in sepsis. We also reported that preventi...

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Bibliografische gegevens
Hoofdauteurs: Graves, Bridget M, Simerly, Thomas, Li, Chuanfu, Williams, David L, Wondergem, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464604/
https://ncbi.nlm.nih.gov/pubmed/22715995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-59
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