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Phosphoinositide-3-kinase/akt - dependent signaling is required for maintenance of [Ca(2+)](i,)I(Ca), and Ca(2+) transients in HL-1 cardiomyocytes
The phosphoinositide 3-kinases (PI3K/Akt) dependent signaling pathway plays an important role in cardiac function, specifically cardiac contractility. We have reported that sepsis decreases myocardial Akt activation, which correlates with cardiac dysfunction in sepsis. We also reported that preventi...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464604/ https://ncbi.nlm.nih.gov/pubmed/22715995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-59 |
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