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Phosphoinositide-3-kinase/akt - dependent signaling is required for maintenance of [Ca(2+)](i,)I(Ca), and Ca(2+) transients in HL-1 cardiomyocytes

The phosphoinositide 3-kinases (PI3K/Akt) dependent signaling pathway plays an important role in cardiac function, specifically cardiac contractility. We have reported that sepsis decreases myocardial Akt activation, which correlates with cardiac dysfunction in sepsis. We also reported that preventi...

詳細記述

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書誌詳細
主要な著者: Graves, Bridget M, Simerly, Thomas, Li, Chuanfu, Williams, David L, Wondergem, Robert
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464604/
https://ncbi.nlm.nih.gov/pubmed/22715995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-59
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