Á lódáil...
A Novel Approach to Recovery of Function of Mutant Proteins by Slowing Down Translation
Protein homeostasis depends on a balance of translation, folding, and degradation. Here, we demonstrate that mild inhibition of translation results in a dramatic and disproportional reduction in production of misfolded polypeptides in mammalian cells, suggesting an improved folding of newly synthesi...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Biochemistry and Molecular Biology
2012
|
| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464534/ https://ncbi.nlm.nih.gov/pubmed/22902621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.397307 |
| Clibeanna: |
Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!
|