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Activation of Transcription Factor MEF2D by Bis(3)-cognitin Protects Dopaminergic Neurons and Ameliorates Parkinsonian Motor Defects
Parkinson disease (PD) is characterized by the selective demise of dopaminergic (DA) neurons in the substantial nigra pars compacta. Dysregulation of transcriptional factor myocyte enhancer factor 2D (MEF2D) has been implicated in the pathogenic process in in vivo and in vitro models of PD. Here, we...
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Główni autorzy: | , , , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Biochemistry and Molecular Biology
2012
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464532/ https://ncbi.nlm.nih.gov/pubmed/22891246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.367540 |
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