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Degradomics Reveals That Cleavage Specificity Profiles of Caspase-2 and Effector Caspases Are Alike

Caspase-2 is considered an initiator caspase because its long prodomain contains a CARD domain that allows its recruitment and activation in several complexes by homotypic death domain-fold interactions. Because little is known about the function and specificity of caspase-2 and its physiological su...

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Detalhes bibliográficos
Main Authors: Wejda, Magdalena, Impens, Francis, Takahashi, Nozomi, Van Damme, Petra, Gevaert, Kris, Vandenabeele, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464509/
https://ncbi.nlm.nih.gov/pubmed/22825847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.384552
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