Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes

The aspartate-specific cysteine protease caspase-1 is activated by the inflammasomes and is responsible for the proteolytic maturation of the cytokines IL-1β and IL-18 during infection and inflammation. To discover new caspase-1 substrates, we made use of a proteome-wide gel-free differential peptid...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi, Van Damme, Petra, Vanden Berghe, Tom, Vanoverberghe, Isabel, Vandekerckhove, Joël, Vandenabeele, Peter, Gevaert, Kris, Núñez, Gabriel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2008
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596343/
https://ncbi.nlm.nih.gov/pubmed/18667412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800132-MCP200
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