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Bioconjugation and Detection of Lactosamine Moiety using α1, 3-Galactosyltransferase Mutants That Transfer C2-modified Galactose with a Chemical Handle
Studies on wild-type and mutant glycosyltransferases have shown that they can transfer modified sugars with a versatile chemical handle, such as keto or azido group, that can be used for conjugation chemistry and detection of glycan residues on glycoconjugates. To detect the most prevalent glycan ep...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464485/ https://ncbi.nlm.nih.gov/pubmed/19245254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800534r |
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