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Bioconjugation and Detection of Lactosamine Moiety using α1, 3-Galactosyltransferase Mutants That Transfer C2-modified Galactose with a Chemical Handle

Studies on wild-type and mutant glycosyltransferases have shown that they can transfer modified sugars with a versatile chemical handle, such as keto or azido group, that can be used for conjugation chemistry and detection of glycan residues on glycoconjugates. To detect the most prevalent glycan ep...

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Detalhes bibliográficos
Main Authors: Pasek, Marta, Ramakrishnan, Boopathy, Boeggeman, Elizabeth, Manzoni, Maria, Waybright, Timothy J., Qasba, Pradman K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464485/
https://ncbi.nlm.nih.gov/pubmed/19245254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800534r
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