Atoh1 governs the migration of post-mitotic neurons that shape respiratory effectiveness at birth and chemoresponsiveness in adulthood

Hindbrain neuronal networks serving respiratory, proprioceptive, and arousal functions share a developmental requirement for the bHLH transcription factor Atoh1. Loss of Atoh1 in mice results in respiratory failure and neonatal lethality; however, the neuronal identity and mechanism by which Atoh1-d...

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Hlavní autoři: Huang, Wei-Hsiang, Tupal, Srinivasan, Huang, Teng-Wei, Ward, Christopher S., Neul, Jeffery L., Klisch, Tiemo J., Gray, Paul A., Zoghbi, Huda Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464459/
https://ncbi.nlm.nih.gov/pubmed/22958821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.06.027
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