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Synthesis and biological activity of a profluorescent analogue of coenzyme B12.

We describe here the synthesis and chemical properties of linear(lin)-benzoadenosylcobalamin, a coenzyme B12 analogue that has a laterally extended nucleoside in the upper axial position. It is an effective competitive inhibitor of ribonucleotide reductase from Lactobacillus leichmannii. lin-Benzoad...

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Detaylı Bibliyografya
Asıl Yazarlar: Rosendahl, M S, Omann, G M, Leonard, N J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1982
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC346444/
https://ncbi.nlm.nih.gov/pubmed/7048307
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