Characterization of [LeuB-24]- and [LeuB-25]-insulin analogues. Receptor binding and biological activity.

Human [LeuB-24]- and [LeuB-25]-insulins were semi-synthesized from porcine insulin by an enzyme-assisted coupling method. The receptor-binding ability of [LeuB-24]- and [LeuB-25]-insulins was 30--48% and 2--5% respectively of that of human insulin. There was no significant difference in degradation...

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Hauptverfasser: Kobayashi, M, Ohgaku, S, Iwasaki, M, Maegawa, H, Shigeta, Y, Inouye, K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1158628/
https://ncbi.nlm.nih.gov/pubmed/6756393
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