cAMP STIMULATES THE UBIQUITIN/PROTEASOME PATHWAY IN RAT SPINAL CORD NEURONS

Proteasome impairment and accumulation of ubiquitinated proteins are implicated in neurodegeneration associated with different forms of spinal cord injury. We show herein that elevating cAMP in rat spinal cord neurons increases 26S proteasome activity in a protein kinase A-dependent manner. Treating...

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Bibliographic Details
Main Authors: Myeku, Natura, Wang, Hu, Figueiredo-Pereira, Maria E.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464398/
https://ncbi.nlm.nih.gov/pubmed/22982149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.051
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