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cAMP STIMULATES THE UBIQUITIN/PROTEASOME PATHWAY IN RAT SPINAL CORD NEURONS

Proteasome impairment and accumulation of ubiquitinated proteins are implicated in neurodegeneration associated with different forms of spinal cord injury. We show herein that elevating cAMP in rat spinal cord neurons increases 26S proteasome activity in a protein kinase A-dependent manner. Treating...

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Bibliografische gegevens
Hoofdauteurs: Myeku, Natura, Wang, Hu, Figueiredo-Pereira, Maria E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464398/
https://ncbi.nlm.nih.gov/pubmed/22982149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.051
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