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cAMP STIMULATES THE UBIQUITIN/PROTEASOME PATHWAY IN RAT SPINAL CORD NEURONS

Proteasome impairment and accumulation of ubiquitinated proteins are implicated in neurodegeneration associated with different forms of spinal cord injury. We show herein that elevating cAMP in rat spinal cord neurons increases 26S proteasome activity in a protein kinase A-dependent manner. Treating...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Myeku, Natura, Wang, Hu, Figueiredo-Pereira, Maria E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464398/
https://ncbi.nlm.nih.gov/pubmed/22982149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.051
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