Activation of the ATM-Snail pathway promotes breast cancer metastasis

The DNA damage response (DDR) is critical for the maintenance of genetic stability and serves as an anti-cancer barrier during early tumorigenesis. However, the role of the DDR in tumor progression and metastasis is less known. Here, we demonstrate that the ATM kinase, one of the critical DDR elemen...

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Autori principali: Sun, Mianen, Guo, Xiaojing, Qian, Xiaolong, Wang, Haibo, Yang, Chunying, Brinkman, Kathryn L., Serrano-Gonzalez, Monica, Jope, Richard S., Zhou, Binhua, Engler, David A., Zhan, Ming, Wong, Stephen T.C., Fu, Li, Xu, Bo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464396/
https://ncbi.nlm.nih.gov/pubmed/22923499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjs048
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