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Activation of the Connective Tissue Growth Factor (CTGF)-Transforming Growth Factor β 1 (TGF-β 1) Axis in Hepatitis C Virus-Expressing Hepatocytes

BACKGROUND: The pro-fibrogenic cytokine connective tissue growth factor (CTGF) plays an important role in the development and progression of fibrosis in many organ systems, including liver. However, its role in the pathogenesis of hepatitis C virus (HCV)-induced liver fibrosis remains unclear. METHO...

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Detalhes bibliográficos
Main Authors: Nagaraja, Tirumuru, Chen, Li, Balasubramanian, Anuradha, Groopman, Jerome E., Ghoshal, Kalpana, Jacob, Samson T., Leask, Andrew, Brigstock, David R., Anand, Appakkudal R., Ganju, Ramesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464290/
https://ncbi.nlm.nih.gov/pubmed/23056332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046526
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