Activation of the Connective Tissue Growth Factor (CTGF)-Transforming Growth Factor β 1 (TGF-β 1) Axis in Hepatitis C Virus-Expressing Hepatocytes

BACKGROUND: The pro-fibrogenic cytokine connective tissue growth factor (CTGF) plays an important role in the development and progression of fibrosis in many organ systems, including liver. However, its role in the pathogenesis of hepatitis C virus (HCV)-induced liver fibrosis remains unclear. METHO...

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Bibliografiske detaljer
Main Authors: Nagaraja, Tirumuru, Chen, Li, Balasubramanian, Anuradha, Groopman, Jerome E., Ghoshal, Kalpana, Jacob, Samson T., Leask, Andrew, Brigstock, David R., Anand, Appakkudal R., Ganju, Ramesh K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464290/
https://ncbi.nlm.nih.gov/pubmed/23056332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046526
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