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Cytosolic Malic Enzyme 1 (ME1) Mediates High Fat Diet-Induced Adiposity, Endocrine Profile, and Gastrointestinal Tract Proliferation-Associated Biomarkers in Male Mice

BACKGROUND: Obesity and associated hormonal disturbances are risk factors for colon cancer. Cytosolic Malic Enzyme (ME1) generates NADPH used for lipogenesis in gastrointestinal (GI), liver and adipose tissues. We have reported that inclusion of soy protein isolate (SPI) in the diet lowered body fat...

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Bibliographic Details
Main Authors: Al-Dwairi, Ahmed, Pabona, John Mark P., Simmen, Rosalia C. M., Simmen, Frank A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464285/
https://ncbi.nlm.nih.gov/pubmed/23056418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046716
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