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Dysfunctional Behavioral Modulation of Corticostriatal Communication in the R6/2 Mouse Model of Huntington’s Disease

BACKGROUND: In Huntington’s disease (HD), motor symptoms develop prior to the widespread loss of neurons in striatum and cerebral cortex. The aim of this study was to examine dysfunctional patterns of corticostriatal communication during spontaneously occurring behaviors in a transgenic mouse model...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hong, S. Lee, Cossyleon, Desirée, Hussain, Wajeeha A., Walker, Lauren J., Barton, Scott J., Rebec, George V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464283/
https://ncbi.nlm.nih.gov/pubmed/23056565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047026
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