Negative Regulation of NF-κB by the ING4 Tumor Suppressor in Breast Cancer

Nuclear Factor kappa B (NF-κB) is a key mediator of normal immune response but contributes to aggressive cancer cell phenotypes when aberrantly activated. Here we present evidence that the Inhibitor of Growth 4 (ING4) tumor suppressor negatively regulates NF-κB in breast cancer. We surveyed primary...

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Autors principals: Byron, Sara A., Min, Elizabeth, Thal, Tanya S., Hostetter, Galen, Watanabe, Aprill T., Azorsa, David O., Little, Tanya H., Tapia, Coya, Kim, Suwon
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464231/
https://ncbi.nlm.nih.gov/pubmed/23056468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046823
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