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The ING4 Tumor Suppressor Attenuates NF-κB Activity at the Promoters of Target Genes

The NF-κB family mediates immune and inflammatory responses. In many cancers, NF-κB is constitutively activated and induces the expression of genes that facilitate tumorigenesis. ING4 is a tumor suppressor that is absent or mutated in several cancers. Herein, we demonstrate that in human gliomas, NF...

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Detalhes bibliográficos
Main Authors: Nozell, Susan, Laver, Travis, Moseley, Dorothy, Nowoslawski, Lisa, DeVos, Marijke, Atkinson, George P., Harrison, Keith, Nabors, L. Burton, Benveniste, Etty N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573235/
https://ncbi.nlm.nih.gov/pubmed/18779315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00697-08
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