Molecular Mechanism for the Dual Alcohol Modulation of Cys-loop Receptors

Cys-loop receptors constitute a superfamily of pentameric ligand-gated ion channels (pLGICs), including receptors for acetylcholine, serotonin, glycine and γ-aminobutyric acid. Several bacterial homologues have been identified that are excellent models for understanding allosteric binding of alcohol...

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Bibliographische Detailangaben
Hauptverfasser: Murail, Samuel, Howard, Rebecca J., Broemstrup, Torben, Bertaccini, Edward J., Harris, R. Adron, Trudell, James R., Lindahl, Erik
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464191/
https://ncbi.nlm.nih.gov/pubmed/23055913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002710
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