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Aging and regulated protein degradation: who has the UPPer hand?

In all cells, protein degradation is a constant, ongoing process that is critical for cell survival and repair. The ubiquitin/proteasome pathway (UPP) is the major proteolytic pathway that degrades intracellular proteins in a regulated manner. It plays critical roles in many cellular processes and d...

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Detalhes bibliográficos
Main Authors: Vernace, Vita A., Schmidt-Glenewinkel, Thomas, Figueiredo-Pereira, Maria E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464091/
https://ncbi.nlm.nih.gov/pubmed/17681036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2007.00329.x
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