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Aging perturbs 26S proteasome assembly in Drosophila melanogaster

Aging is associated with loss of quality control in protein turnover. The ubiquitin-proteasome pathway is critical to this quality control process as it degrades mutated and damaged proteins. We identified a unique aging-dependent mechanism that contributes to proteasome dysfunction in Drosophila me...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vernace, Vita A., Arnaud, Lisette, Schmidt-Glenewinkel, Thomas, Figueiredo-Pereira, Maria E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435146/
https://ncbi.nlm.nih.gov/pubmed/17413001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.06-6751com
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