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Aging perturbs 26S proteasome assembly in Drosophila melanogaster
Aging is associated with loss of quality control in protein turnover. The ubiquitin-proteasome pathway is critical to this quality control process as it degrades mutated and damaged proteins. We identified a unique aging-dependent mechanism that contributes to proteasome dysfunction in Drosophila me...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435146/ https://ncbi.nlm.nih.gov/pubmed/17413001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.06-6751com |
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