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The Structure of Human Argonaute-2 in Complex with miR-20a

Argonaute proteins lie at the heart of the RNA-induced silencing complex (RISC), wherein they use small RNA guides to recognize targets. Initial insight into the architecture of Argonautes came from studies of prokaryotic proteins, revealing a crescent-shaped base made up of the amino-terminal, PAZ,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Elkayam, Elad, Kuhn, Claus-D., Tocilj, Ante, Haase, Astrid D., Greene, Emily M., Hannon, Gregory J., Joshua-Tor, Leemor
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464090/
https://ncbi.nlm.nih.gov/pubmed/22682761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.017
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