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The Structure of Human Argonaute-2 in Complex with miR-20a
Argonaute proteins lie at the heart of the RNA-induced silencing complex (RISC), wherein they use small RNA guides to recognize targets. Initial insight into the architecture of Argonautes came from studies of prokaryotic proteins, revealing a crescent-shaped base made up of the amino-terminal, PAZ,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3464090/ https://ncbi.nlm.nih.gov/pubmed/22682761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.017 |
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