Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia

The homozygous WHHL (Watanabe heritable hyperlipidemic) rabbit displays either no or only minimal low density lipoprotein (LDL) receptor activity on cultured fibroblasts and liver membranes and has therefore been proposed as an animal model for human familial hypercholesterolemia. To assess the impa...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Bilheimer, David W., Watanabe, Yoshio, Kita, Toru
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1982
Soggetti:	Biological Sciences: Medical Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6285345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.10.3305
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