Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia

The homozygous WHHL (Watanabe heritable hyperlipidemic) rabbit displays either no or only minimal low density lipoprotein (LDL) receptor activity on cultured fibroblasts and liver membranes and has therefore been proposed as an animal model for human familial hypercholesterolemia. To assess the impa...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bilheimer, David W., Watanabe, Yoshio, Kita, Toru
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1982
Assuntos:	Biological Sciences: Medical Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6285345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.10.3305
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