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Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia

The homozygous WHHL (Watanabe heritable hyperlipidemic) rabbit displays either no or only minimal low density lipoprotein (LDL) receptor activity on cultured fibroblasts and liver membranes and has therefore been proposed as an animal model for human familial hypercholesterolemia. To assess the impa...

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Détails bibliographiques
Auteurs principaux: Bilheimer, David W., Watanabe, Yoshio, Kita, Toru
Format: Artigo
Langue:Inglês
Publié: 1982
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC346404/
https://ncbi.nlm.nih.gov/pubmed/6285345
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