Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia

The homozygous WHHL (Watanabe heritable hyperlipidemic) rabbit displays either no or only minimal low density lipoprotein (LDL) receptor activity on cultured fibroblasts and liver membranes and has therefore been proposed as an animal model for human familial hypercholesterolemia. To assess the impa...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Bilheimer, David W., Watanabe, Yoshio, Kita, Toru
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1982
Materias:	Biological Sciences: Medical Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6285345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.10.3305
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