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The EWS/FLI Oncogene Drives Changes in Cellular Morphology, Adhesion, and Migration in Ewing Sarcoma

Ewing sarcoma is a tumor of the bone and soft tissue caused by the expression of a translocation-derived oncogenic transcription factor, EWS/FLI. Overt metastases are associated with a poor prognosis in Ewing sarcoma, but patients without overt metastases frequently harbor micrometastatic disease at...

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Detalhes bibliográficos
Main Authors: Chaturvedi, Aashi, Hoffman, Laura M., Welm, Alana L., Lessnick, Stephen L., Beckerle, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463921/
https://ncbi.nlm.nih.gov/pubmed/23050043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912457024
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