The LIM Protein Zyxin Binds CARP-1 and Promotes Apoptosis

Por Hervy, Martial, Hoffman, Laura M., Jensen, Christopher C., Smith, Mark, Beckerle, Mary C.
Publicado em 2010

Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

Por Hoffman, Laura M., Jensen, Christopher C., Chaturvedi, Aashi, Yoshigi, Masaaki, Beckerle, Mary C.
Publicado em 2012

Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement

Por Yoshigi, Masaaki, Hoffman, Laura M., Jensen, Christopher C., Yost, H. Joseph, Beckerle, Mary C.
Publicado em 2005

The EWS/FLI Oncogene Drives Changes in Cellular Morphology, Adhesion, and Migration in Ewing Sarcoma

Por Chaturvedi, Aashi, Hoffman, Laura M., Welm, Alana L., Lessnick, Stephen L., Beckerle, Mary C.
Publicado em 2012

EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma

Por Fadul, John, Bell, Russell, Hoffman, Laura M., Beckerle, Mary C., Engel, Michael E., Lessnick, Stephen L.
Publicado no Genes Cancer (2015)

Genetic ablation of zyxin causes Mena/VASP mislocalization, increased motility, and deficits in actin remodeling

Por Hoffman, Laura M., Jensen, Christopher C., Kloeker, Susanne, Wang, C.-L. Albert, Yoshigi, Masaaki, Beckerle, Mary C.
Publicado em 2006

LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain

Por Smith, Mark A., Blankman, Elizabeth, Deakin, Nicholas O., Hoffman, Laura M., Jensen, Christopher C., Turner, Christopher E., Beckerle, Mary C.
Publicado em 2013

Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth

Por Sankar, Savita, Theisen, Emily R., Bearss, Jared, Mulvihill, Timothy, Hoffman, Laura M., Sorna, Venkataswamy, Beckerle, Mary C., Sharma, Sunil, Lessnick, Stephen L.
Publicado em 2014

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma

Por Chaturvedi, Aashi, Hoffman, Laura M., Jensen, Christopher C., Lin, Yi-Chun, Grossmann, Allie H., Randall, R. Lor, Lessnick, Stephen L., Welm, Alana L., Beckerle, Mary C.
Publicado em 2014

Supervillin modulation of focal adhesions involving TRIP6/ZRP-1

Por Takizawa, Norio, Smith, Tara C., Nebl, Thomas, Crowley, Jessica L., Palmieri, Stephen J., Lifshitz, Lawrence M., Ehrhardt, Anka G., Hoffman, Laura M., Beckerle, Mary C., Luna, Elizabeth J.
Publicado em 2006

Targeted Disruption of the Murine zyxin Gene

Por Hoffman, Laura M., Nix, David A., Benson, Beverly, Boot-Hanford, Ray, Gustafsson, Erika, Jamora, Colin, Menzies, A. Sheila, Goh, Keow Lin, Jensen, Christopher C., Gertler, Frank B., Fuchs, Elaine, Fässler, Reinhard, Beckerle, Mary C.
Publicado em 2003

Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility

Por Piccolo, Stephen R, Hoffman, Laura M, Conner, Thomas, Shrestha, Gajendra, Cohen, Adam L, Marks, Jeffrey R, Neumayer, Leigh A, Agarwal, Cori A, Beckerle, Mary C, Andrulis, Irene L, Spira, Avrum E, Moos, Philip J, Buys, Saundra S, Johnson, William Evan, Bild, Andrea H
Publicado no Mol Syst Biol (2016)