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In Vivo-Formed versus Preformed Metabolite Kinetics of trans-Resveratrol-3-sulfate and trans-Resveratrol-3-glucuronide

Metabolites in safety testing have gained a lot of attention recently. Regulatory agencies have suggested that the kinetics of preformed and in vivo-formed metabolites are comparable. This subject has been a topic of debate. We have compared the kinetics of in vivo-formed with preformed metabolites....

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Hlavní autoři: Sharan, Satish, Iwuchukwu, Otito F., Canney, Daniel J., Zimmerman, Cheryl L., Nagar, Swati
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463825/
https://ncbi.nlm.nih.gov/pubmed/22807110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.112.046417
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