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Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies
Trans -3,5,4′-trihydroxystilbene (trans-resveratrol, RES) exhibits very low bioavailability due to extensive conjugative metabolism. Whether RES metabolites exhibit pharmacologic activity is of great interest. The present study aimed at synthesis of monoconjugates of RES – the 3- and 4′ monosulfates...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299880/ https://ncbi.nlm.nih.gov/pubmed/22342060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2011.12.006 |
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