Mechanism of action of dichloro-beta-D-ribofuranosylbenzimidazole: effect on in vitro transcription.

The adenosine analog 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) and its mono- and triphosphate derivatives inhibit RNA polymerase II-specific transcription in an extract of whole HeLa cells. The analog does not inhibit RNA polymerase III-specific adenovirus VA RNA transcription in the wh...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Zandomeni, R, Mittleman, B, Bunick, D, Ackerman, S, Weinmann, R
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1982
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.10.3167
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