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Mechanism of action of dichloro-beta-D-ribofuranosylbenzimidazole: effect on in vitro transcription.
The adenosine analog 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) and its mono- and triphosphate derivatives inhibit RNA polymerase II-specific transcription in an extract of whole HeLa cells. The analog does not inhibit RNA polymerase III-specific adenovirus VA RNA transcription in the wh...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1982
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6954467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.10.3167 |
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